Immortality begins with Becoming an Alchemy Grandmaster - Chapter 330 - 163: Sky Roc Transformation, I Have

The NPC sets out on a journey to defeat the Demon Lord, joined by beautiful girls he meets along the way.---This is an NSFW story, so if you're under 18, turn back now, son. No NTR, and no full-on Yuri. There might be slight Yuri—like girls kissing and stuff during threesomes—but it's not that kind of Yuri where the girls fall in love with each other while in a relationship with the MC.---

Her – a glutton without troubles or worries who crossed over and became a young fat chick with a deep vengefulness.

Him – a young master of the number one power; a two-faced man with elegance and charming, good looks; he is the chosen one of the former saint god and a man who will only bend his back for her alone.

This domineering crossover’s slogan is, ‘Don’t touch if it is this sister’s, put it there if it isn’t this sister’s!’

…watch how the Domineering Glutton and the Two-Faced Venerate Emperor create sparks as they meet and collide, stirring the whole Spirit Treasure Continent into turmoil, how they fall for each other and how they kill each other, how life and death severs love.

- Description from Novelupdates

Ryan «Quicksave» Romano is an eccentric adventurer with a strange power: he can create a save-point in time and redo his life whenever he dies. Arriving in New Rome, the glitzy capital of sin of a rebuilding Europe, he finds the city torn between mega-corporations, sponsored heroes, superpowered criminals, and true monsters. It’s a time of chaos, where potions can grant the power to rule the world and dangers lurk everywhere.

Zhou Yu was ordered to enter the city and get married. Even though my wife didn't like me, my father-in-law disapproved of me, my colleagues always wanted to bully me, and the bad guys were always looking to take me down, but touch me, that's fine, touch my wife, that's not. Whoever lays a hand on her, I'll take down. I fought until the whole world bowed down, then returned to the village with my wife in glory!