MTL - My Senpai Knows Magic - Chapter 163 plague

A Di [legitimate-born] daughter of a noble house turns into an abandoned daughter. No father to dote on her, no mother to love her, no problem. She uses one silver needle to save a dying man. What’s so unusual about a medical injection? She roams all over the world with a scalpel in her hand. Cutting throats, cutting open abdomens, cutting open skulls to mend bones. With amazing medical skills and ethics, she gathers a flock of officials, obtains the will of heavens, gains public favor, and receives Taizi’s [Crown Prince] doting. In the midst of a powerful momentum, her cheap father comes to reunite. She coldly refuses to go home or acknowledge ancestors.

“I was abandoned by you over and over again. Now you want to use familial affection to coax me back. You don’t want to recognize this daughter. My heart is cold, I want to leave. Beat it, father!”

- Description from Novelupdates

Originally born from a wealthy family, she ends up leading a vagrant life for fifteen years. However, when she is eventually found by her family, she falls into another devious plot and eventually dies tragically.

When Orion is mysteriously transmigrated into a primitive world where sex and other goods and services can be bartered for, he is determined to make the most of his second chance at life.

But as he delves deeper into this dangerous world filled with temptation and magic, Orion must use his wit, charm, and thirst for adventure to survive and make the most of his second chance at life.

“With my knowledge, give me a fulcrum on which to place it and I shall move the world!”