MTL - Naruto’s Hidden Orphan - Chapter 88 The boundary that can't get out.

Violet skies, a world undergoing massive changes, a deficient moon, interlinking voids…
When the world experienced a cataclysmic event,the majority of living things ceased to exist. Although humanity survived by hiding in the last safe zones, humans had to face mutated dire beasts and colossal source beasts that could break through the space barrier and enter the earth at any second.
Luo Yunyang, a young man who grew up in those calamitous times, obtained an attribute regulator and set out to walk the path of supremacy!

- Description from novelupdates

Sam Sanderson is envied by many for his job, however he himself didn't seem to like it much.

Due to his expertise in nanotechnology he was tasked with monitoring the state the Valkyries, humanity's strongest weapons who all just happen to be made into gorgeous females.

Forbidden from even touching any of them, Sam spends his days in agony watching flowers he couldn't hope to touch. However one day all of that seemed to change.

Vahn was an atypical youth. Due to a rare mutation, his blood had the potential to target and attack ailments within the human body. Touted as a universal cure, people had elevated his status above the norm and given him the classification "Panacea". In the media, he was hailed as a great hero who would usher in a new era or human wellness. However, behind the scenes things weren't so bright. Being a unique individual, Vahn spent his entire youth locked up in a lab with various scientists and research teams using his body and blood to perform endless amounts of experiments. The only solace in his suffering was the various anime and manga made available to him between experiments. He often imagined himself as the protagonist in a world of his own, finally in control of his own destiny. For years he nurtured this desire, until at the age of 14 he died when an organization had tried to kidnap him from the lab...

During this chaotic era, the darkness engulfs all.
In a struggle of fire and death, despair shrouds the continent.
The line between fantasy and reality becomes blurred as a speckle of starlight penetrates the night sky.
But is it enough to reverse the downfall and fate? To regain the lost glory?

Rhode is a famed player in the game “Dragon Soul Continent”. There, he leads the strongest player guild in the game, the Starlight Guild. Just as he defeats the last BOSS, the Void Dragon, he unexpectedly awoke in a world identical to the game.

As the Summoner Swordsman returns to the continent, waves will be cast in the rivers of fate. Can he face the coming chaos and avert the destruction of the continent?

- Description from Novelupdates