Revenge of the Phoenix Beauty - Chapter 36: Approval

Vahn was an atypical youth. Due to a rare mutation, his blood had the potential to target and attack ailments within the human body. Touted as a universal cure, people had elevated his status above the norm and given him the classification "Panacea". In the media, he was hailed as a great hero who would usher in a new era or human wellness. However, behind the scenes things weren't so bright. Being a unique individual, Vahn spent his entire youth locked up in a lab with various scientists and research teams using his body and blood to perform endless amounts of experiments. The only solace in his suffering was the various anime and manga made available to him between experiments. He often imagined himself as the protagonist in a world of his own, finally in control of his own destiny. For years he nurtured this desire, until at the age of 14 he died when an organization had tried to kidnap him from the lab...

No family, no power, no inheritance — a thrice-lacking protagonist. Just how will the seed rise up from the mud?

- Description from Novelupdates

Huang Dan’s pain nerve is innately different from the ordinary people. A little tore in his skin can cause him to sweat all over his body painfully to the point of him unable to make a word out.

Somehow, he began to cross world, following Mr. System to do the tasks…

In the first world, Huang Dan realizes what it means to die painfully and to live to die again.

TL’s summary:
MC suddenly transmigrated and is bind to a system, requiring him to solve mysteries. Born with a higher degree of pain sensitivity, he met different people in the different worlds and learns what kind of emotion smiling is.

- Description from Novelupdates