Transformed into Cosmic Horror in a Sci-Fi Universe - Chapter 111

QiLeren had just cleared the bad ending of «The Nightmare Games» when his laptop died well before its time. His luck seemed to follow him as he was transported, along with the other passengers, to a hospital following an accident between his bus and a truck. Upon waking in a transfusion hall rather than a ward, QiLeren felt a familiar sense of dread as he took in the hospital that held no trace of other people…

Book 1 of a Trilogy

- Description from Novelupdates

He is a young man without a spirit root. It is believed that this denies him the chance at cultivation. However, a mysterious lady imparts a Supreme Demon Classic to him and from then on, he starts his path of cultivation.
He undergoes a total transformation to emerge as the most fearsome and powerful fiendish demon in his era, that even immortals and fiends are fearful of him, and saints are at his beck and call.
Mastering the Supreme Demon Classic is the turning point in his life. He is able to unleash his immense and divine power from within, illuminating the entire universe!

A boy wakes up with omnitrix as a X-GENE